NAD+ Makes Its Way Into Skin Care
NAD+ (short for nicotinamide adenine dinucleotide) has captured the beauty world’s attention, shifting from laboratory research to skin-care formulations. According to Vogue, emerging studies suggest NAD+ plays a pivotal role in maintaining skin elasticity, promoting collagen and elastin synthesis, improving hydration, and supporting the microvascular network that helps deliver vital nutrients to the skin .
NAD+ and Skin Care
NAD+ is finding its way into skin care products. What are the benefits?
This coenzyme also serves as a critical activator for sirtuins, which are the proteins that govern inflammation response and cellular repair. Naturally, as NAD+ levels decline with age, the skin begins to show visible signs of aging. That’s where NAD+ has entered the beauty conversation with renewed force.
Spurred by these potential effects, skincare brands are now formulating serums, creams, and essences infused with topical NAD+. Some early adopters and celebrities tout a “cellular glow-up,” and products featuring NAD+ are touted as a gentler alternative to traditional anti‑aging actives like retinol. Still, Vogue reporters caution that NAD+ is both unstable and difficult to incorporate into topical formats, as it oxidizes easily, is hard to absorb, and degrades when exposed to air.
Despite the buzz around NAD+ skincare, the real gold standard for effectiveness remains intravenous (IV) delivery. IV NAD+ ensures nearly 100% absorption, maximizing bioavailability, and delivering systemic effects, such as enhanced cellular energy, better skin clarity, reduced inflammation, and improved vitality, which can’t be matched by topical applications alone.
In short: while NAD+-infused skincare offers an intriguing new frontier in beauty, IV NAD+ therapy remains the superior method for unlocking the coenzyme’s full regenerative and skin-rejuvenating potential.